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Medication Math

Dosage calculations, IV flow rates, conversions, and practice drills

Formula Reference

Keep these four core formulas handy — they cover the vast majority of clinical dosage calculations.

Dose Formula

Dose = (Desired ÷ Available) × Quantity

Example: Order 500mg, have 250mg/5mL → (500÷250)×5 = 10mL

Use when: Calculating liquid medication doses from stock concentration.

IV Flow Rate

mL/hr = Volume (mL) ÷ Time (hrs)

Example: 1000mL over 8hrs → 1000÷8 = 125 mL/hr

Use when: Setting IV pump rates for continuous infusions.

Drops per Minute

gtt/min = (Volume × Drop Factor) ÷ Time (min)

Example: 500mL × 15gtt/mL ÷ 240min = 31 gtt/min

Use when: Manual IV infusions using gravity drip sets.

Weight‑Based

Dose = Weight (kg) × Dose per kg

Example: 22kg × 15mg/kg = 330mg, then convert to mL

Use when: Pediatric and weight‑dependent medication dosing.

Practice Problems

Work through clinical calculation scenarios — select an answer and submit to see the full solution.

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Problem 1

The provider orders amoxicillin 500 mg PO. The pharmacy supplies amoxicillin 250 mg/5 mL. How many mL should the nurse administer?

Problem 2

Order: 1000 mL NS to infuse over 8 hours. What is the mL/hr rate?

Problem 3

Order: 500 mL LR over 4 hours. Drop factor: 15 gtt/mL. Calculate gtt/min.

Problem 4

Order: acetaminophen 15 mg/kg PO for a child weighing 22 kg. Pharmacy supplies 160 mg/5 mL. How many mL?

Problem 5

Order: levothyroxine 0.075 mg PO daily. Available: 25 mcg tablets. How many tablets?

Problem 6

A patient is receiving 20 gtt/min of NS with a drop factor of 10 gtt/mL. What is the mL/hr rate?

Problem 7

Calculate the body surface area (BSA) for a patient who is 165 cm tall and weighs 68 kg. Use the Mosteller formula: BSA = √[(height cm × weight kg) / 3600]. Round to the nearest hundredth.

Problem 8

A child weighs 18 kg. The safe dosage range is 30–50 mg/kg/day divided q8h. The provider orders 350 mg q8h. Is the ordered dose within the safe range?

Problem 9

Order: 500 mL NS to infuse at 75 mL/hr. The infusion starts at 0900. At what time (military time) will the infusion be completed?

Problem 10

A powdered medication label reads: 'Add 4.5 mL NS to yield 500 mg/5 mL.' The provider orders 350 mg IM. How many mL should the nurse administer?

Problem 11

If 250 mg of a drug is in 5 mL of solution, how many mL contain 175 mg? Solve using ratio-proportion.

Problem 12

Order: ceftriaxone 50 mg/kg IV q12h for a child weighing 33 lb. Pharmacy supplies ceftriaxone 1 g/10 mL after reconstitution. How many mL per dose? (Round to the nearest tenth.)

Complete the first 4 problems to unlock the rest

FromToConversion
1 kglb2.2 lb
1 gmg1000 mg
1 mgmcg1000 mcg
1 LmL1000 mL
1 tspmL5 mL
1 tbspmL15 mL
1 ozmL30 mL
1 inchcm2.54 cm